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Ah, Dunning-Kruger, you are so cruel. You know, that psychological quirk of humans in which confidence starts high with lack of expertise, only to fall quickly, like on a stomach-wrenching roller-coaster, as knowledge is gained. Such was our recent project exploring surveillance using genomic sequencing. While we knew we were far from experts in the field of genomic sequencing, we had high confidence that we would learn enough to accomplish something useful.